Angiotensin II receptor type 1 on granulosa and thecal cells of rabbit preovulatory follicles
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چکیده
منابع مشابه
Involvement of theca cells and steroids in the regulation of granulosa cell apoptosis in rabbit preovulatory follicles.
Follicular atresia is characterized by a rapid loss of granulosa cells and, to a lesser extent, theca cells, via apoptosis. The aim of this study was to investigate the possible involvement of theca cell secretions in the regulation of apoptosis of rabbit granulosa cells. The annexin-V binding method based on externalization of phosphatidylserine to the outer layer of plasma membrane during apo...
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Angiotensin II (AngII) is best known for its role in blood pressure regulation, but it also has documented actions in the reproductive system. There are two AngII receptors, type 1 (AGTR1) and type 2 (AGTR2). AGTR2 mediates the noncardiovascular effects of AngII and is expressed in the granulosa cell layer in rodents and is associated with follicle atresia. In contrast, expression of AGTR2 is r...
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materials and methods: 32 new zealand rabbits were randomly divided into three groups: control group, high-cholesterol group and losartan group. the level of weights, serum lipid levels and inflammatory factors, such as il-6 and hs c-reactive protein were detected before the losartan intervention and two months after the losartan intervention respectively. the content of angii was detected on l...
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To examine timed changes in the morphology of theca interna and granulosa cells of rabbit preovulatory follicles, mature female rabbits were injected with100 IU per kg of human chorionic gonadotropin (hCG) and follicles larger than1mn in diameter were excised for light and electron microscopic studies before and3, 6, 9and 12hr after hCG injection. Spindle-shaped theca interna cells had been tra...
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In the 1970s, a series of observations demonstrated that angiotensin II has deleterious effects on the heart and kidney and that patients with high levels of plasma renin activity are at a higher risk of developing stroke or myocardial infarction than those with low plasma renin activity.1,2 Thereafter, the development of pharmacological probes that block the renin-angiotensin system helped def...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Biomembranes
سال: 1996
ISSN: 0005-2736
DOI: 10.1016/s0005-2736(96)00134-4